Microhomology-mediated End Joining and Homologous Recombination share the initial end resection step to repair DNA double-strand breaks in mammalian cells

Microhomology-mediated end joining (MMEJ) is a major pathway for Ku-independent alternative nonhomologous end joining, which contributes to chromosomal translocations and telomere fusions, but the underlying mechanism of MMEJ in mammalian cells is not well understood. In this study, we demonstrated...

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Detaylı Bibliyografya
Asıl Yazarlar: Truong, Lan N., Li, Yongjiang, Shi, Linda Z., Hwang, Patty Yi-Hwa, He, Jing, Wang, Hailong, Razavian, Niema, Berns, Michael W., Wu, Xiaohua
Materyal Türü: Artigo
Dil:Inglês
Baskı/Yayın Bilgisi: National Academy of Sciences 2013
Konular:
Biological Sciences
Online Erişim:https://ncbi.nlm.nih.gov/pmc/articles/PMC3651503/
https://ncbi.nlm.nih.gov/pubmed/23610439
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.1213431110
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