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Ptch2 mediates the Shh response in Ptch1(−/−) cells
The Hedgehog (Hh) signaling response is regulated by the interaction of three key components that include the sonic hedgehog (Shh) ligand, its receptor patched 1 (Ptch1) and the pathway activator smoothened (Smo). Under the prevailing model of Shh pathway activation, the binding of Shh to Ptch1 (the...
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| Main Authors: | , , , , |
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| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
The Company of Biologists
2014
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC4199129/ https://ncbi.nlm.nih.gov/pubmed/25085974 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1242/dev.110056 |
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