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Ptch1 and Gli regulate Shh signalling dynamics via multiple mechanisms
In the vertebrate neural tube, the morphogen Sonic Hedgehog (Shh) establishes a characteristic pattern of gene expression. Here we quantify the Shh gradient in the developing mouse neural tube and show that while the amplitude of the gradient increases over time, the activity of the pathway transcri...
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| Publicado no: | Nat Commun |
|---|---|
| Main Authors: | , , , , , , |
| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
Nature Pub. Group
2015
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC4396374/ https://ncbi.nlm.nih.gov/pubmed/25833741 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/ncomms7709 |
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