β-Cell-Specific Glucocorticoid Reactivation Attenuates Inflammatory β-Cell Destruction

Progression and severity of type 1 diabetes is dependent upon inflammatory induction of nitric oxide production and consequent pancreatic β-cell damage. Glucocorticoids (GCs) are highly effective anti-inflammatory agents but have been precluded in type 1 diabetes and in islet transplantation protoco...

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Detalhes bibliográficos
Main Authors: Liu, Xiaoxia, Turban, Sophie, Carter, Roderick N., Ahmad, Shakil, Ramage, Lynne, Webster, Scott P., Walker, Brian R., Seckl, Jonathan R., Morton, Nicholas M.
Formato: Artigo
Idioma:Inglês
Publicado em: Frontiers Media S.A. 2014
Assuntos:
Endocrinology
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4196588/
https://ncbi.nlm.nih.gov/pubmed/25352830
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3389/fendo.2014.00165
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