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Proteasome inhibition reverses hedgehog inhibitor and taxane resistance in ovarian cancer

The goal of this study was to determine whether combined targeted therapies, specifically those against the Notch, hedgehog and ubiquitin-proteasome pathways, could overcome ovarian cancer chemoresistance. Chemoresistant ovarian cancer cells were exposed to gamma-secretase inhibitors (GSI-I, Compoun...

Πλήρης περιγραφή

Αποθηκεύτηκε σε:
Λεπτομέρειες βιβλιογραφικής εγγραφής
Κύριοι συγγραφείς: Steg, Adam D., Burke, Mata R., Amm, Hope M., Katre, Ashwini A., Dobbin, Zachary C., Jeong, Dae Hoon, Landen, Charles N.
Μορφή: Artigo
Γλώσσα:Inglês
Έκδοση: Impact Journals LLC 2014
Θέματα:
Διαθέσιμο Online:https://ncbi.nlm.nih.gov/pmc/articles/PMC4196184/
https://ncbi.nlm.nih.gov/pubmed/25216523
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