Proteasome inhibition reverses hedgehog inhibitor and taxane resistance in ovarian cancer

The goal of this study was to determine whether combined targeted therapies, specifically those against the Notch, hedgehog and ubiquitin-proteasome pathways, could overcome ovarian cancer chemoresistance. Chemoresistant ovarian cancer cells were exposed to gamma-secretase inhibitors (GSI-I, Compoun...

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Detaylı Bibliyografya
Asıl Yazarlar: Steg, Adam D., Burke, Mata R., Amm, Hope M., Katre, Ashwini A., Dobbin, Zachary C., Jeong, Dae Hoon, Landen, Charles N.
Materyal Türü: Artigo
Dil:Inglês
Baskı/Yayın Bilgisi: Impact Journals LLC 2014
Konular:
Research Paper
Online Erişim:https://ncbi.nlm.nih.gov/pmc/articles/PMC4196184/
https://ncbi.nlm.nih.gov/pubmed/25216523
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