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Smoothened Antagonists Reverse Taxane Resistance in Ovarian Cancer

The hedgehog (HH) pathway has been implicated in the formation and maintenance of a variety of malignancies, including ovarian cancer; however, it is unknown whether HH signaling is involved in ovarian cancer chemoresistance. The goal of this study was to determine the effects of antagonizing the HH...

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Main Authors: Steg, Adam D., Katre, Ashwini A., Bevis, Kerri S., Ziebarth, Angela, Dobbin, Zachary C., Shah, Monjri M., Alvarez, Ronald D., Landen, Charles N.
Formato: Artigo
Idioma:Inglês
Publicado: 2012
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Acceso en liña:https://ncbi.nlm.nih.gov/pmc/articles/PMC3392529/
https://ncbi.nlm.nih.gov/pubmed/22553355
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1158/1535-7163.MCT-11-1058
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