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Stem cell pathways contribute to clinical chemoresistance in ovarian cancer

PURPOSE: Within heterogeneous tumors, subpopulations often labeled cancer stem cells (CSCs) have been identified that have enhanced tumorigenicity and chemoresistance in ex vivo models. However, whether these populations are more capable of surviving chemotherapy in de novo tumors is unknown. EXPERI...

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Détails bibliographiques
Auteurs principaux: Steg, Adam D., Bevis, Kerri S., Katre, Ashwini A., Ziebarth, Angela, Alvarez, Ronald D., Zhang, Kui, Conner, Michael, Landen, Charles N.
Format: Artigo
Langue:Inglês
Publié: 2011
Sujets:
Accès en ligne:https://ncbi.nlm.nih.gov/pmc/articles/PMC3271164/
https://ncbi.nlm.nih.gov/pubmed/22142828
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1158/1078-0432.CCR-11-2188
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