Stem cell pathways contribute to clinical chemoresistance in ovarian cancer

PURPOSE: Within heterogeneous tumors, subpopulations often labeled cancer stem cells (CSCs) have been identified that have enhanced tumorigenicity and chemoresistance in ex vivo models. However, whether these populations are more capable of surviving chemotherapy in de novo tumors is unknown. EXPERI...

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Bibliographic Details
Main Authors: Steg, Adam D., Bevis, Kerri S., Katre, Ashwini A., Ziebarth, Angela, Alvarez, Ronald D., Zhang, Kui, Conner, Michael, Landen, Charles N.
Format: Artigo
Language:Inglês
Published: 2011
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Article
Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC3271164/
https://ncbi.nlm.nih.gov/pubmed/22142828
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1158/1078-0432.CCR-11-2188
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