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Stem cell pathways contribute to clinical chemoresistance in ovarian cancer

PURPOSE: Within heterogeneous tumors, subpopulations often labeled cancer stem cells (CSCs) have been identified that have enhanced tumorigenicity and chemoresistance in ex vivo models. However, whether these populations are more capable of surviving chemotherapy in de novo tumors is unknown. EXPERI...

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Detalhes bibliográficos
Main Authors: Steg, Adam D., Bevis, Kerri S., Katre, Ashwini A., Ziebarth, Angela, Alvarez, Ronald D., Zhang, Kui, Conner, Michael, Landen, Charles N.
Formato: Artigo
Idioma:Inglês
Publicado em: 2011
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Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3271164/
https://ncbi.nlm.nih.gov/pubmed/22142828
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1158/1078-0432.CCR-11-2188
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