Farnesyltransferase Inhibitors Reverse Taxane Resistance

The combination of farnesyltransferase inhibitors (FTIs) and taxanes has been shown to result in potent antiproliferative and antimitotic synergy. Recent phase I and II clinical trials have shown that this combination shows clinical activity in taxane-refractory or taxane-resistant cancer patients....

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Main Authors: Marcus, Adam I., O’Brate, Aurora M., Buey, Ruben M., Zhou, Jun, Thomas, Shala, Khuri, Fadlo R., Andreu, Jose Manuel, Díaz, Fernando, Giannakakou, Paraskevi
Formato: Artigo
Idioma:Inglês
Publicado: 2006
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Article
Acceso en liña:https://ncbi.nlm.nih.gov/pmc/articles/PMC1861825/
https://ncbi.nlm.nih.gov/pubmed/16951201
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1158/0008-5472.CAN-06-0699
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