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The Protein Farnesyltransferase Regulates HDAC6 Activity in a Microtubule-dependent Manner
The cytoplasmic deacetylase HDAC6 is an important regulator of cellular pathways that include response to stress, protein folding, microtubule stability, and cell migration, thus representing an attractive target for cancer chemotherapy. However, little is known about its upstream regulation. Our pr...
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Main Authors: | , , , , , , |
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Formato: | Artigo |
Idioma: | Inglês |
Publicado em: |
American Society for Biochemistry and Molecular Biology
2009
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Assuntos: | |
Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC2665085/ https://ncbi.nlm.nih.gov/pubmed/19228685 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1074/jbc.M808708200 |
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