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The Protein Farnesyltransferase Regulates HDAC6 Activity in a Microtubule-dependent Manner

The cytoplasmic deacetylase HDAC6 is an important regulator of cellular pathways that include response to stress, protein folding, microtubule stability, and cell migration, thus representing an attractive target for cancer chemotherapy. However, little is known about its upstream regulation. Our pr...

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Detalhes bibliográficos
Main Authors: Zhou, Jun, Vos, Chantal Chanel, Gjyrezi, Ada, Yoshida, Minoru, Khuri, Fadlo R., Tamanoi, Fuyuhiko, Giannakakou, Paraskevi
Formato: Artigo
Idioma:Inglês
Publicado em: American Society for Biochemistry and Molecular Biology 2009
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC2665085/
https://ncbi.nlm.nih.gov/pubmed/19228685
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1074/jbc.M808708200
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