The Protein Farnesyltransferase Regulates HDAC6 Activity in a Microtubule-dependent Manner

The cytoplasmic deacetylase HDAC6 is an important regulator of cellular pathways that include response to stress, protein folding, microtubule stability, and cell migration, thus representing an attractive target for cancer chemotherapy. However, little is known about its upstream regulation. Our pr...

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Bibliografische gegevens
Hoofdauteurs: Zhou, Jun, Vos, Chantal Chanel, Gjyrezi, Ada, Yoshida, Minoru, Khuri, Fadlo R., Tamanoi, Fuyuhiko, Giannakakou, Paraskevi
Formaat: Artigo
Taal:Inglês
Gepubliceerd in: American Society for Biochemistry and Molecular Biology 2009
Onderwerpen:
Protein Synthesis, Post-Translational Modification, and Degradation
Online toegang:https://ncbi.nlm.nih.gov/pmc/articles/PMC2665085/
https://ncbi.nlm.nih.gov/pubmed/19228685
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1074/jbc.M808708200
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