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Farnesyltransferase inhibitors induce dramatic morphological changes of KNRK cells that are blocked by microtubule interfering agents

Farnesyltransferase inhibitors (FTIs) exhibit the remarkable ability to inhibit transformed phenotypes of a variety of human cancer cell lines and to block the growth of cancer cells in a number of animal model systems. In this paper, we report that the addition of FTI to v-K-ras- transformed NRK ce...

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Bibliografiska uppgifter
Huvudupphovsmän: Suzuki, Nobutaka, Del Villar, Keith, Tamanoi, Fuyuhiko
Materialtyp: Artigo
Språk:Inglês
Publicerad: The National Academy of Sciences 1998
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Länkar:https://ncbi.nlm.nih.gov/pmc/articles/PMC27923/
https://ncbi.nlm.nih.gov/pubmed/9724732
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