Mitotic Kinesin Inhibitors Induce Mitotic Arrest and Cell Death in Taxol-resistant and -sensitive Cancer Cells*

Por Marcus, Adam I., Peters, Ulf, Thomas, Shala L., Garrett, Sarah, Zelnak, Amelia, Kapoor, Tarun M., Giannakakou, Paraskevi
Publicado em 2005

EF24, a novel curcumin analog, disrupts the microtubule cytoskeleton and inhibits HIF-1

Por Thomas, Shala L., Zhong, Diansheng, Zhou, Wei, Malik, Sanna, Liotta, Dennis, Snyder, James P., Hamel, Ernest, Giannakakou, Paraskevi
Publicado em 2008

Activation of the p38- pathway by a novel monoketone curcumin analog, EF24, suggests a potential combination strategy

Por Thomas, Shala L., Zhao, Jing, Li, Zijian, Lou, Bin, Du, Yuhong, Purcell, Jamie, Snyder, James P., Khuri, Fadlo R., Liotta, Dennis, Fu, Haian
Publicado em 2010

Farnesyltransferase Inhibitors Reverse Taxane Resistance

Por Marcus, Adam I., O’Brate, Aurora M., Buey, Ruben M., Zhou, Jun, Thomas, Shala, Khuri, Fadlo R., Andreu, Jose Manuel, Díaz, Fernando, Giannakakou, Paraskevi
Publicado em 2006

Inhibition of IκB Kinase-Nuclear Factor-κB Signaling Pathway by 3,5-Bis(2-flurobenzylidene)piperidin-4-one (EF24), a Novel Monoketone Analog of Curcumin

Por Kasinski, Andrea L., Du, Yuhong, Thomas, Shala L., Zhao, Jing, Sun, Shi-Yong, Khuri, Fadlo R., Wang, Cun-Yu, Shoji, Mamoru, Sun, Aiming, Snyder, James P., Liotta, Dennis, Fu, Haian
Publicado em 2008

Evaluation of the Tubulin-Bound Paclitaxel Conformation: Synthesis, Biology and SAR Studies of C-4 to C-3′ Bridged Paclitaxel Analogs

Por Ganesh, Thota, Yang, Chao, Norris, Andrew, Glass, Tom, Bane, Susan, Ravindra, Rudravajhala, Banerjee, Abhijit, Metaferia, Belhu, Thomas, Shala L., Giannakakou, Paraskevi, Alcaraz, Ana A., Lakdawala, Ami S., Snyder, James P., Kingston, David G. I.
Publicado em 2007