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The use of hedgehog antagonists in cancer therapy: a comparison of clinical outcomes and gene expression analyses

Hedgehog (HH) signaling, a critical developmental pathway, has been implicated in cancer initiation and progression. With vismodegib and sonidegib having been approved for clinical use, increasing numbers of HH inhibitors alone and in combination with chemotherapies are in clinical trials. Here we h...

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Bibliografske podrobnosti
izdano v:Cancer Biol Ther
Main Authors: Booker, Burthia E., Steg, Adam D., Kovac, Stefan, Landen, Charles N., Amm, Hope M.
Format: Artigo
Jezik:Inglês
Izdano: Taylor & Francis 2020
Teme:
Online dostop:https://ncbi.nlm.nih.gov/pmc/articles/PMC7583710/
https://ncbi.nlm.nih.gov/pubmed/32914706
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1080/15384047.2020.1806640
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