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Ligation activity of fragmented ribozymes in frozen solution: implications for the RNA world

A vexing difficulty of the RNA world hypothesis is how RNA molecules of significant complexity could ever have evolved given their susceptibility to degradation. One way degradation might have been reduced is through low temperature. Here we report that truncated and fragmented derivatives of the ha...

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Détails bibliographiques
Publié dans:Nucleic Acids Res
Auteurs principaux: Vlassov, Alexander V., Johnston, Brian H., Landweber, Laura F., Kazakov, Sergei A.
Format: Artigo
Langue:Inglês
Publié: Oxford University Press 2004
Sujets:
Accès en ligne:https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC419604/
https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/15161960/
https://ncbi.nlm.nih.govhttps://doi.org/10.1093/nar/gkh601
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