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Chemical syntheses of inhibitory substrates of the RNA–RNA ligation reaction catalyzed by the hairpin ribozyme

The chemical syntheses of RNA oligomers containing modifications on the 5′-carbon of the 5′-terminal nucleoside for crystallographic and mechanistic studies of the hairpin ribozyme are reported. Phosphoramidites 4 and 8 were prepared and used in solid phase syntheses of RNA oligomers containing the...

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Detalles Bibliográficos
Main Authors: Massey, Archna P., Sigurdsson, Snorri Th.
Formato: Artigo
Idioma:Inglês
Publicado: Oxford University Press 2004
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Acceso en liña:https://ncbi.nlm.nih.gov/pmc/articles/PMC390368/
https://ncbi.nlm.nih.gov/pubmed/15064361
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/nar/gkh517
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