Chemical syntheses of inhibitory substrates of the RNA–RNA ligation reaction catalyzed by the hairpin ribozyme

The chemical syntheses of RNA oligomers containing modifications on the 5′-carbon of the 5′-terminal nucleoside for crystallographic and mechanistic studies of the hairpin ribozyme are reported. Phosphoramidites 4 and 8 were prepared and used in solid phase syntheses of RNA oligomers containing the...

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Publicado en:	Nucleic Acids Res
Autores principales:	Massey, Archna P., Sigurdsson, Snorri Th.
Formato:	Artigo
Lenguaje:	Inglês
Publicado:	Oxford University Press 2004
Materias:	Articles
Acceso en línea:	https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC390368/ https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/15064361/ https://ncbi.nlm.nih.govhttps://doi.org/10.1093/nar/gkh517
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