Prebiotically Plausible RNA Activation Compatible with Ribozyme‐Catalyzed Ligation

RNA‐catalyzed RNA ligation is widely believed to be a key reaction for primordial biology. However, since typical chemical routes towards activating RNA substrates are incompatible with ribozyme catalysis, it remains unclear how prebiotic systems generated and sustained pools of activated building b...

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Detalhes bibliográficos
Publicado no:Angew Chem Int Ed Engl
Main Authors: Song, Emilie Yeonwha, Jiménez, Eddy Ivanhoe, Lin, Huacan, Le Vay, Kristian, Krishnamurthy, Ramanarayanan, Mutschler, Hannes
Formato: Artigo
Idioma:Inglês
Publicado em: John Wiley and Sons Inc. 2020
Assuntos:
Communications
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC7898671/
https://ncbi.nlm.nih.gov/pubmed/33128282
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1002/anie.202010918
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