Prebiotically Plausible RNA Activation Compatible with Ribozyme‐Catalyzed Ligation

RNA‐catalyzed RNA ligation is widely believed to be a key reaction for primordial biology. However, since typical chemical routes towards activating RNA substrates are incompatible with ribozyme catalysis, it remains unclear how prebiotic systems generated and sustained pools of activated building b...

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Foilsithe in:Angew Chem Int Ed Engl
Main Authors: Song, Emilie Yeonwha, Jiménez, Eddy Ivanhoe, Lin, Huacan, Le Vay, Kristian, Krishnamurthy, Ramanarayanan, Mutschler, Hannes
Formáid: Artigo
Teanga:Inglês
Foilsithe: John Wiley and Sons Inc. 2020
Ábhair:
Communications
Rochtain Ar Líne:https://ncbi.nlm.nih.gov/pmc/articles/PMC7898671/
https://ncbi.nlm.nih.gov/pubmed/33128282
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1002/anie.202010918
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