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Non-canonical 3′-5′ Extension of RNA with Prebiotically Plausible Ribonucleoside 2′,3′-Cyclic Phosphates

[Image: see text] Ribonucleoside 2′,3′-cyclic phosphates (N>p’s) are generated by multiple prebiotically plausible processes and are credible building blocks for the assembly of early RNA oligomers. While N>p’s can be polymerized into short RNAs by non-enzymatic processes with variable efficie...

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Veröffentlicht in:J Am Chem Soc
Hauptverfasser: Mutschler, Hannes, Holliger, Philipp
Format: Artigo
Sprache:Inglês
Veröffentlicht: American Chemical Society 2014
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC4333585/
https://ncbi.nlm.nih.gov/pubmed/24660752
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1021/ja4127714
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