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Prebiotically plausible oligoribonucleotide ligation facilitated by chemoselective acetylation

The recent synthesis of pyrimidine ribonucleoside-2′,3′-cyclic phosphates under prebiotically plausible conditions has strengthened the case for the involvement of RNA at an early stage in the origin of life. However, a prebiotic conversion of these weakly activated monomers, and their purine counte...

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Bibliografske podrobnosti
Main Authors: Bowler, Frank R., Chan, Christopher K. W., Duffy, Colm D., Gerland, Béatrice, Islam, Saidul, Powner, Matthew W., Sutherland, John D., Xu, Jianfeng
Format: Artigo
Jezik:Inglês
Izdano: 2013
Teme:
Online dostop:https://ncbi.nlm.nih.gov/pmc/articles/PMC4074891/
https://ncbi.nlm.nih.gov/pubmed/23609088
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/nchem.1626
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