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Prebiotically plausible oligoribonucleotide ligation facilitated by chemoselective acetylation
The recent synthesis of pyrimidine ribonucleoside-2′,3′-cyclic phosphates under prebiotically plausible conditions has strengthened the case for the involvement of RNA at an early stage in the origin of life. However, a prebiotic conversion of these weakly activated monomers, and their purine counte...
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| Hauptverfasser: | , , , , , , , |
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| Format: | Artigo |
| Sprache: | Inglês |
| Veröffentlicht: |
2013
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| Schlagworte: | |
| Online Zugang: | https://ncbi.nlm.nih.gov/pmc/articles/PMC4074891/ https://ncbi.nlm.nih.gov/pubmed/23609088 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/nchem.1626 |
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