Prebiotically Plausible RNA Activation Compatible with Ribozyme‐Catalyzed Ligation

RNA‐catalyzed RNA ligation is widely believed to be a key reaction for primordial biology. However, since typical chemical routes towards activating RNA substrates are incompatible with ribozyme catalysis, it remains unclear how prebiotic systems generated and sustained pools of activated building b...

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Vydáno v:Angew Chem Int Ed Engl
Hlavní autoři: Song, Emilie Yeonwha, Jiménez, Eddy Ivanhoe, Lin, Huacan, Le Vay, Kristian, Krishnamurthy, Ramanarayanan, Mutschler, Hannes
Médium: Artigo
Jazyk:Inglês
Vydáno: John Wiley and Sons Inc. 2020
Témata:
Communications
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC7898671/
https://ncbi.nlm.nih.gov/pubmed/33128282
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1002/anie.202010918
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