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Ligation activity of fragmented ribozymes in frozen solution: implications for the RNA world

A vexing difficulty of the RNA world hypothesis is how RNA molecules of significant complexity could ever have evolved given their susceptibility to degradation. One way degradation might have been reduced is through low temperature. Here we report that truncated and fragmented derivatives of the ha...

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Main Authors: Vlassov, Alexander V., Johnston, Brian H., Landweber, Laura F., Kazakov, Sergei A.
פורמט: Artigo
שפה:Inglês
יצא לאור: Oxford University Press 2004
נושאים:
גישה מקוונת:https://ncbi.nlm.nih.gov/pmc/articles/PMC419604/
https://ncbi.nlm.nih.gov/pubmed/15161960
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/nar/gkh601
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