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Hairpin ribozyme-antisense RNA constructs can act as molecular lassos

We have developed a novel class of antisense agents, RNA Lassos, which are capable of binding to and circularizing around complementary target RNAs. The RNA Lasso consists of a fixed sequence derived from the hairpin ribozyme and an antisense segment whose size and sequence can be varied to base pai...

תיאור מלא

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מידע ביבליוגרפי
Main Authors: Dallas, Anne, Balatskaya, Svetlana V., Kuo, Tai-Chih, Ilves, Heini, Vlassov, Alexander V., Kaspar, Roger L., Kisich, Kevin O., Kazakov, Sergei A., Johnston, Brian H.
פורמט: Artigo
שפה:Inglês
יצא לאור: Oxford University Press 2008
נושאים:
RNA
גישה מקוונת:https://ncbi.nlm.nih.gov/pmc/articles/PMC2588507/
https://ncbi.nlm.nih.gov/pubmed/18953032
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/nar/gkn637
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