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Ligation of the hairpin ribozyme in cis induced by freezing and dehydration

Although reducing the temperature slows most chemical reactions, freezing can stimulate some reactions by mechanisms that are only partially understood. Here we show that freezing stimulates the self-ligation (circularization) of linear forms of the hairpin ribozyme (HPR) containing 2′,3′-cyclic pho...

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Detalhes bibliográficos
Main Authors: KAZAKOV, SERGEI A., BALATSKAYA, SVETLANA V., JOHNSTON, BRIAN H.
Formato: Artigo
Idioma:Inglês
Publicado em: Copyright 2006 by RNA Society 2006
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC1383583/
https://ncbi.nlm.nih.gov/pubmed/16495237
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1261/rna.2123506
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