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Ligation of the hairpin ribozyme in cis induced by freezing and dehydration

Although reducing the temperature slows most chemical reactions, freezing can stimulate some reactions by mechanisms that are only partially understood. Here we show that freezing stimulates the self-ligation (circularization) of linear forms of the hairpin ribozyme (HPR) containing 2′,3′-cyclic pho...

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Autors principals: KAZAKOV, SERGEI A., BALATSKAYA, SVETLANA V., JOHNSTON, BRIAN H.
Format: Artigo
Idioma:Inglês
Publicat: Copyright 2006 by RNA Society 2006
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Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC1383583/
https://ncbi.nlm.nih.gov/pubmed/16495237
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1261/rna.2123506
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