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Ligation of the hairpin ribozyme in cis induced by freezing and dehydration

Although reducing the temperature slows most chemical reactions, freezing can stimulate some reactions by mechanisms that are only partially understood. Here we show that freezing stimulates the self-ligation (circularization) of linear forms of the hairpin ribozyme (HPR) containing 2′,3′-cyclic pho...

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Autori principali: KAZAKOV, SERGEI A., BALATSKAYA, SVETLANA V., JOHNSTON, BRIAN H.
Natura: Artigo
Lingua:Inglês
Pubblicazione: Copyright 2006 by RNA Society 2006
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Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC1383583/
https://ncbi.nlm.nih.gov/pubmed/16495237
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1261/rna.2123506
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