Complete, gene-specific siRNA libraries: Production and expression in mammalian cells

Short interfering RNAs (siRNAs) are widely used to silence the expression of specific genes. Current practice for designing effective siRNAs is to use algorithms based on sequence-efficacy correlations; however, there are many highly effective sequences that these algorithms do not anticipate. To en...

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Autors principals: SEYHAN, ATTILA A., VLASSOV, ALEXANDER V., ILVES, HEINI, EGRY, LEVENTE, KASPAR, ROGER L., KAZAKOV, SERGEI A., JOHNSTON, BRIAN H.
Format: Artigo
Idioma:Inglês
Publicat: Copyright 2005 by RNA Society 2005
Matèries:
Method
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC1370768/
https://ncbi.nlm.nih.gov/pubmed/15840823
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1261/rna.7285805
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