Complete, gene-specific siRNA libraries: Production and expression in mammalian cells

Short interfering RNAs (siRNAs) are widely used to silence the expression of specific genes. Current practice for designing effective siRNAs is to use algorithms based on sequence-efficacy correlations; however, there are many highly effective sequences that these algorithms do not anticipate. To en...

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Main Authors: SEYHAN, ATTILA A., VLASSOV, ALEXANDER V., ILVES, HEINI, EGRY, LEVENTE, KASPAR, ROGER L., KAZAKOV, SERGEI A., JOHNSTON, BRIAN H.
Formato: Artigo
Idioma:Inglês
Publicado em: Copyright 2005 by RNA Society 2005
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Method
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC1370768/
https://ncbi.nlm.nih.gov/pubmed/15840823
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1261/rna.7285805
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