Carregant...
Upf1 Phosphorylation Triggers Translational Repression during Nonsense-Mediated mRNA Decay
In mammalian cells, nonsense-mediated mRNA decay (NMD) generally requires that translation terminates sufficiently upstream of a post-splicing exon junction complex (EJC) during a pioneer round of translation. The subsequent binding of Upf1 to the EJC triggers Upf1 phosphorylation. We provide eviden...
Guardat en:
| Autors principals: | , , , , , |
|---|---|
| Format: | Artigo |
| Idioma: | Inglês |
| Publicat: |
2008
|
| Matèries: | |
| Accés en línia: | https://ncbi.nlm.nih.gov/pmc/articles/PMC4193665/ https://ncbi.nlm.nih.gov/pubmed/18423202 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.cell.2008.02.030 |
| Etiquetes: |
Afegir etiqueta
Sense etiquetes, Sigues el primer a etiquetar aquest registre!
|