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UPFront and center in RNA decay: UPF1 in nonsense-mediated mRNA decay and beyond

Nonsense-mediated mRNA decay (NMD), which is arguably the best-characterized translation-dependent regulatory pathway in mammals, selectively degrades mRNAs as a means of post-transcriptional gene control. Control can be for the purpose of ensuring the quality of gene expression. Alternatively, cont...

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Detalhes bibliográficos
Publicado no:RNA
Main Authors: Kim, Yoon Ki, Maquat, Lynne E.
Formato: Artigo
Idioma:Inglês
Publicado em: Cold Spring Harbor Laboratory Press 2019
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC6426291/
https://ncbi.nlm.nih.gov/pubmed/30655309
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1261/rna.070136.118
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