Nonsense-mediated mRNA decay factor UPF1 promotes aggresome formation

Nonsense-mediated mRNA decay (NMD) typifies an mRNA surveillance pathway. Because NMD necessitates a translation event to recognize a premature termination codon on mRNAs, truncated misfolded polypeptides (NMD-polypeptides) could potentially be generated from NMD substrates as byproducts. Here, we s...

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Detalhes bibliográficos
Publicado no:Nat Commun
Main Authors: Park, Yeonkyoung, Park, Joori, Hwang, Hyun Jung, Kim, Byungju, Jeong, Kwon, Chang, Jeeyoon, Lee, Jong-Bong, Kim, Yoon Ki
Formato: Artigo
Idioma:Inglês
Publicado em: Nature Publishing Group UK 2020
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Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC7305299/
https://ncbi.nlm.nih.gov/pubmed/32561765
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/s41467-020-16939-6
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