Nonsense-mediated mRNA decay factor UPF1 promotes aggresome formation

Nonsense-mediated mRNA decay (NMD) typifies an mRNA surveillance pathway. Because NMD necessitates a translation event to recognize a premature termination codon on mRNAs, truncated misfolded polypeptides (NMD-polypeptides) could potentially be generated from NMD substrates as byproducts. Here, we s...

Disgrifiad llawn

Wedi'i Gadw mewn:
Manylion Llyfryddiaeth
Cyhoeddwyd yn:Nat Commun
Prif Awduron: Park, Yeonkyoung, Park, Joori, Hwang, Hyun Jung, Kim, Byungju, Jeong, Kwon, Chang, Jeeyoon, Lee, Jong-Bong, Kim, Yoon Ki
Fformat: Artigo
Iaith:Inglês
Cyhoeddwyd: Nature Publishing Group UK 2020
Pynciau:
Article
Mynediad Ar-lein:https://ncbi.nlm.nih.gov/pmc/articles/PMC7305299/
https://ncbi.nlm.nih.gov/pubmed/32561765
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/s41467-020-16939-6
Tagiau: Ychwanegu Tag
Dim Tagiau, Byddwch y cyntaf i dagio'r cofnod hwn!

Eitemau Tebyg