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Nonsense-mediated mRNA decay factor UPF1 promotes aggresome formation
Nonsense-mediated mRNA decay (NMD) typifies an mRNA surveillance pathway. Because NMD necessitates a translation event to recognize a premature termination codon on mRNAs, truncated misfolded polypeptides (NMD-polypeptides) could potentially be generated from NMD substrates as byproducts. Here, we s...
Enregistré dans:
| Publié dans: | Nat Commun |
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| Auteurs principaux: | , , , , , , , |
| Format: | Artigo |
| Langue: | Inglês |
| Publié: |
Nature Publishing Group UK
2020
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| Sujets: | |
| Accès en ligne: | https://ncbi.nlm.nih.gov/pmc/articles/PMC7305299/ https://ncbi.nlm.nih.gov/pubmed/32561765 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/s41467-020-16939-6 |
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