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Staufen1 and UPF1 exert opposite actions on the replacement of the nuclear cap-binding complex by eIF4E at the 5′ end of mRNAs

Newly synthesized mRNAs are exported from the nucleus to cytoplasm with a 5′-cap structure bound by the nuclear cap-binding complex (CBC). During or after export, the CBC should be properly replaced by cytoplasmic cap-binding protein eIF4E for efficient protein synthesis. Nonetheless, little is know...

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Wedi'i Gadw mewn:
Manylion Llyfryddiaeth
Cyhoeddwyd yn:Nucleic Acids Res
Prif Awduron: Jeong, Kwon, Ryu, Incheol, Park, Joori, Hwang, Hyun Jung, Ha, Hongseok, Park, Yeonkyoung, Oh, Sang Taek, Kim, Yoon Ki
Fformat: Artigo
Iaith:Inglês
Cyhoeddwyd: Oxford University Press 2019
Pynciau:
Mynediad Ar-lein:https://ncbi.nlm.nih.gov/pmc/articles/PMC6753478/
https://ncbi.nlm.nih.gov/pubmed/31361897
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/nar/gkz643
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