Allergic Airway Inflammation Decreases Lung Bacterial Burden following Acute Klebsiella pneumoniae Infection in a Neutrophil- and CCL8-Dependent Manner

The Th17 cytokines interleukin-17A (IL-17A), IL-17F, and IL-22 are critical for the lung immune response to a variety of bacterial pathogens, including Klebsiella pneumoniae. Th2 cytokine expression in the airways is a characteristic feature of asthma and allergic airway inflammation. The Th2 cytoki...

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Main Authors: Dulek, Daniel E., Newcomb, Dawn C., Goleniewska, Kasia, Cephus, Jaqueline, Zhou, Weisong, Reiss, Sara, Toki, Shinji, Ye, Fei, Zaynagetdinov, Rinat, Sherrill, Taylor P., Blackwell, Timothy S., Moore, Martin L., Boyd, Kelli L., Kolls, Jay K., Peebles, R. Stokes
Format: Artigo
Jezik:Inglês
Izdano: American Society for Microbiology 2014
Teme:
Host Response and Inflammation
Online dostop:https://ncbi.nlm.nih.gov/pmc/articles/PMC4187810/
https://ncbi.nlm.nih.gov/pubmed/24958709
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/IAI.00035-14
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