Allergic Airway Inflammation Decreases Lung Bacterial Burden following Acute Klebsiella pneumoniae Infection in a Neutrophil- and CCL8-Dependent Manner

The Th17 cytokines interleukin-17A (IL-17A), IL-17F, and IL-22 are critical for the lung immune response to a variety of bacterial pathogens, including Klebsiella pneumoniae. Th2 cytokine expression in the airways is a characteristic feature of asthma and allergic airway inflammation. The Th2 cytoki...

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Autors principals: Dulek, Daniel E., Newcomb, Dawn C., Goleniewska, Kasia, Cephus, Jaqueline, Zhou, Weisong, Reiss, Sara, Toki, Shinji, Ye, Fei, Zaynagetdinov, Rinat, Sherrill, Taylor P., Blackwell, Timothy S., Moore, Martin L., Boyd, Kelli L., Kolls, Jay K., Peebles, R. Stokes
Format: Artigo
Idioma:Inglês
Publicat: American Society for Microbiology 2014
Matèries:
Host Response and Inflammation
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC4187810/
https://ncbi.nlm.nih.gov/pubmed/24958709
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/IAI.00035-14
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