Endogenous PGI(2) signaling through IP inhibits neutrophilic lung inflammation in LPS-induced acute lung injury mice model

Endogenous prostaglandin I(2) (PGI(2)) has inhibitory effects on immune responses against pathogens or allergens; however, the immunomodulatory activity of endogenous PGI(2) signaling in endotoxin-induced inflammation is unknown. To test the hypothesis that endogenous PGI(2) down-regulates endotoxin...

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Detalhes bibliográficos
Publicado no:Prostaglandins Other Lipid Mediat
Main Authors: Toki, Shinji, Zhou, Weisong, Goleniewska, Kasia, Reiss, Sara, Dulek, Daniel E., Newcomb, Dawn C., Lawson, William E., Peebles, R. Stokes
Formato: Artigo
Idioma:Inglês
Publicado em: 2018
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Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC5970997/
https://ncbi.nlm.nih.gov/pubmed/29660395
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.prostaglandins.2018.04.001
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