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The PGI(2) analog cicaprost inhibits IL-33-induced Th2 responses, IL-2 production, and CD25 expression in mouse CD4(+) T cells

IL-33 has pleiotropic functions in immune responses and promotes the development of allergic diseases and asthma. IL-33 induces Th2 differentiation and enhances type 2 cytokine production by CD4(+) T cells. However, the regulation of IL-33-driven type 2 cytokine responses is not fully defined. In th...

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Publicado en:J Immunol
Autores principales: Zhou, Weisong, Zhang, Jian, Toki, Shinji, Goleniewska, Kasia, Johnson, Marc O., Bloodworth, Melissa H., Newcomb, Dawn C., Peebles, R. Stokes
Formato: Artigo
Lenguaje:Inglês
Publicado: 2018
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Acceso en línea:https://ncbi.nlm.nih.gov/pmc/articles/PMC6162094/
https://ncbi.nlm.nih.gov/pubmed/30127087
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.4049/jimmunol.1700605
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