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Plk1 Phosphorylation of PTEN Causes a Tumor-Promoting Metabolic State
One outcome of activation of the phosphatidylinositol 3-kinase (PI3K) pathway is increased aerobic glycolysis, but the upstream signaling events that regulate the PI3K pathway, and thus the Warburg effect, are elusive. Increasing evidence suggests that Plk1, a cell cycle regulator, is also involved...
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| Main Authors: | , , , , , , , , , , |
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| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
American Society for Microbiology
2014
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC4187734/ https://ncbi.nlm.nih.gov/pubmed/25047839 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/MCB.00814-14 |
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