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Plk1 phosphorylation of IRS2 prevents premature mitotic exit via AKT inactivation

Insulin receptor substrate (IRS) proteins play important roles by acting as a platform in transducing signals from transmembrane receptors upon growth factor stimulation. Although tyrosine phosphorylation on IRS proteins plays critical roles in signal transduction, phosphorylation of IRS proteins on...

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Detalhes bibliográficos
Publicado no:Biochemistry
Main Authors: Chen, Long, Li, Zhiguo, Ahmad, Nihal, Liu, Xiaoqi
Formato: Artigo
Idioma:Inglês
Publicado em: 2015
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4950874/
https://ncbi.nlm.nih.gov/pubmed/25830382
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1021/acs.biochem.5b00016
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