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RPA phosphorylation facilitates mitotic exit in response to mitotic DNA damage

Human replication protein A (RPA) becomes phosphorylated on the RPA2 subunit by cyclin B-Cdc2 during mitosis, although the functional role of this modification is unclear. We find that this modification stimulates RPA2 to become hyperphosphorylated in response to mitotic DNA damage caused by bleomyc...

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Detalhes bibliográficos
Main Authors: Anantha, Rachel William, Sokolova, Elena, Borowiec, James A.
Formato: Artigo
Idioma:Inglês
Publicado em: National Academy of Sciences 2008
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC2529075/
https://ncbi.nlm.nih.gov/pubmed/18723675
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.0803001105
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