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RPA phosphorylation facilitates mitotic exit in response to mitotic DNA damage

Human replication protein A (RPA) becomes phosphorylated on the RPA2 subunit by cyclin B-Cdc2 during mitosis, although the functional role of this modification is unclear. We find that this modification stimulates RPA2 to become hyperphosphorylated in response to mitotic DNA damage caused by bleomyc...

詳細記述

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書誌詳細
主要な著者: Anantha, Rachel William, Sokolova, Elena, Borowiec, James A.
フォーマット: Artigo
言語:Inglês
出版事項: National Academy of Sciences 2008
主題:
オンライン・アクセス:https://ncbi.nlm.nih.gov/pmc/articles/PMC2529075/
https://ncbi.nlm.nih.gov/pubmed/18723675
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.0803001105
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