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CD28 and CTLA-4 coreceptor expression and signal transduction
T-cell activation is mediated by antigen-specific signals from the TCRζ/CD3 and CD4–CD8–p56lck complexes in combination with additional co-signals provided by coreceptors such as CD28, inducible costimulator (ICOS), cytotoxic T-lymphocyte antigen-4 (CTLA-4), programmed death (PD-1), and others. CD28...
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| Main Authors: | , , |
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| Format: | Artigo |
| Jezik: | Inglês |
| Izdano: |
2009
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| Teme: | |
| Online dostop: | https://ncbi.nlm.nih.gov/pmc/articles/PMC4186963/ https://ncbi.nlm.nih.gov/pubmed/19426212 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1111/j.1600-065X.2009.00770.x |
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