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Cytotoxic T Lymphocyte Antigen 4 and CD28 Modulate Cell Surface Raft Expression in Their Regulation of T Cell Function

Coreceptors CD28 and cytotoxic T lymphocyte antigen (CTLA)-4 have opposing effects on TcR/CD3 activation of T cells. While CD28 enhances and CTLA-4 inhibits activation, the underlying molecular basis of these effects has yet to be established. In this context, ganglioside and cholesterol enriched me...

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Библиографические подробности
Главные авторы: Martin, Margarita, Schneider, Helga, Azouz, Abdallah, Rudd, Christopher E.
Формат: Artigo
Язык:Inglês
Опубликовано: The Rockefeller University Press 2001
Предметы:
Online-ссылка:https://ncbi.nlm.nih.gov/pmc/articles/PMC2193535/
https://ncbi.nlm.nih.gov/pubmed/11733581
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