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Negative Regulation of T Cell Receptor–Lipid Raft Interaction by Cytotoxic T Lymphocyte–associated Antigen 4

Cytotoxic T lymphocyte–associated antigen 4 (CTLA-4) is an essential negative regulator of T cell activation. Recent evidence suggests that CTLA-4 association with the immunological synapse during contact with antigen-presenting cells is important for its inhibitory function. In the present study, w...

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Detalhes bibliográficos
Main Authors: Chikuma, Shunsuke, Imboden, John B., Bluestone, Jeffrey A.
Formato: Artigo
Idioma:Inglês
Publicado em: The Rockefeller University Press 2003
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC2193802/
https://ncbi.nlm.nih.gov/pubmed/12515820
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1084/jem.20021646
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