Cytotoxic T Lymphocyte–associated Antigen 4 (CTLA-4) Can Regulate Dendritic Cell–induced Activation and Cytotoxicity of CD8(+) T Cells Independently of CD4(+)T Cell Help

The mechanisms that regulate the strength and duration of CD8(+) cytotoxic T cell activity determine the effectiveness of an antitumor immune response. To better understand the antitumor effects of anti-cytotoxic T lymphocyte–associated antigen 4 (CTLA-4) antibody treatment, we analyzed the effect o...

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Sparad:
Bibliografiska uppgifter
Huvudupphovsmän: McCoy, Kathy D., Hermans, Ian F., Henry Fraser, J., Le Gros, Graham, Ronchese, Franca
Materialtyp: Artigo
Språk:Inglês
Publicerad: The Rockefeller University Press 1999
Ämnen:
Brief Definitive Reports
Länkar:https://ncbi.nlm.nih.gov/pmc/articles/PMC2193004/
https://ncbi.nlm.nih.gov/pubmed/10190907
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