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CTLA-4 blockade during dendritic cell based booster vaccination influences dendritic cell survival and CTL expansion

Dendritic cells (DCs) are potent antigen-presenting cells and critical for the priming of CD8+ T cells. Therefore the use of these cells as adjuvant cells has been tested in a large number of experimental and clinical vaccination studies, in particular cancer vaccine studies. A number of protocols a...

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Detalhes bibliográficos
Main Authors: Pedersen, Anders E, Ronchese, Franca
Formato: Artigo
Idioma:Inglês
Publicado em: BioMed Central 2007
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC1950502/
https://ncbi.nlm.nih.gov/pubmed/17662155
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/1476-8518-5-9
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