Dendritic Cell Vaccination Combined with CTLA4 Blockade in Patients with Metastatic Melanoma

PURPOSE: Tumor antigen-loaded dendritic cells (DC) are believed to activate antitumor immunity by stimulating T cells, and cytotoxic T lymphocyte-associated antigen 4 (CTLA4)-blocking antibodies should release a key negative regulatory pathway on T cells. The combination was tested in a phase 1 clin...

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Detaylı Bibliyografya
Asıl Yazarlar: Ribas, Antoni, Comin-Anduix, Begoña, Chmielowski, Bartosz, Jalil, Jason, de la Rocha, Pilar, McCannel, Tara A., Ochoa, Maria Teresa, Seja, Elizabeth, Villanueva, Arturo, Oseguera, Denise K., Straatsma, Bradley R., Cochran, Alistair J., Glaspy, John A., Hui, Liu, Marincola, Francesco M., Wang, Ena, Economou, James S., Gomez-Navarro, Jesus
Materyal Türü: Artigo
Dil:Inglês
Baskı/Yayın Bilgisi: 2009
Konular:
Article
Online Erişim:https://ncbi.nlm.nih.gov/pmc/articles/PMC2765061/
https://ncbi.nlm.nih.gov/pubmed/19789309
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1158/1078-0432.CCR-09-1254
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