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Protective Immunity to Nematode Infection Is Induced by CTLA-4 Blockade

The recent observation that neutralization or genetic deletion of the T lymphocyte receptor CTLA-4 allows enhanced T cell reactivity offers new opportunities for immunotherapy against infectious agents. We used a neutralizing antibody to block CTLA-4 interaction with its ligands CD80 and CD86 during...

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Detalhes bibliográficos
Main Authors: McCoy, Kathy, Camberis, Mali, Gros, Graham Le
Formato: Artigo
Idioma:Inglês
Publicado em: The Rockefeller University Press 1997
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC2198990/
https://ncbi.nlm.nih.gov/pubmed/9221747
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