CTLA-4 Blockade Enhances the Immune Response Induced by Mycobacterial Infection but Does Not Lead to Increased Protection

The murine immune response to a pulmonary mycobacterial infection is slow to develop, allowing bacterial numbers to increase in the lung for several weeks after infection. We sought to enhance the protective immune response induced during Mycobacterium bovis BCG infection by administering an antibod...

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Detalhes bibliográficos
Main Authors: Kirman, Joanna, McCoy, Kathy, Hook, Sarah, Prout, Melanie, Delahunt, Brett, Orme, Ian, Frank, Anthony, Le Gros, Graham
Formato: Artigo
Idioma:Inglês
Publicado em: American Society for Microbiology 1999
Assuntos:
Microbial Immunity and Vaccines
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC96655/
https://ncbi.nlm.nih.gov/pubmed/10417139
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