טוען...
Diverse Mechanisms Regulate the Surface Expression of Immunotherapeutic Target CTLA-4
T-cell co-receptor cytotoxic T-cell antigen-4 (CTLA-4) is a critical inhibitory regulator of T-cell immunity and antibody blockade of the co-receptor has been shown to be effective in tumor immunotherapy. Paradoxically, the majority of CTLA-4 is located in intracellular compartments from where it is...
שמור ב:
| הוצא לאור ב: | Front Immunol |
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| Main Authors: | , |
| פורמט: | Artigo |
| שפה: | Inglês |
| יצא לאור: |
Frontiers Media S.A.
2014
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| נושאים: | |
| גישה מקוונת: | https://ncbi.nlm.nih.gov/pmc/articles/PMC4255484/ https://ncbi.nlm.nih.gov/pubmed/25538704 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3389/fimmu.2014.00619 |
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