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Murine regulatory T cells differ from conventional T cells in resisting the CTLA-4 reversal of TCR stop-signal

CTLA-4 inhibits T-cell activation and protects against the development of autoimmunity. We and others previously showed that the coreceptor can induce T-cell motility and shorten dwell times with dendritic cells (DCs). However, it has been unclear whether this property of CTLA-4 affects both convent...

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Bibliografiske detaljer
Main Authors: Lu, Yuning, Schneider, Helga, Rudd, Christopher E.
Format: Artigo
Sprog:Inglês
Udgivet: American Society of Hematology 2012
Fag:
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC3557398/
https://ncbi.nlm.nih.gov/pubmed/23047820
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1182/blood-2012-04-421420
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