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TCR/CD3 mediated stop-signal is decoupled in T-cells from Ctla4 deficient mice
CTLA-4 is a co-receptor that plays a pivotal role in regulating the threshold for T-cell activation. We recently reported that CTLA-4 ligation can over-ride the stop-signal induced by anti-CD3 ligation [Schneider H, Downey J, Smith A, Zinselmeyer BH, Rush C, Brewer JM, et al. Reversal of the TCR sto...
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| 主要な著者: | , , , , |
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| フォーマット: | Artigo |
| 言語: | Inglês |
| 出版事項: |
2007
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| 主題: | |
| オンライン･アクセス: | https://ncbi.nlm.nih.gov/pmc/articles/PMC4186962/ https://ncbi.nlm.nih.gov/pubmed/17964663 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.imlet.2007.09.004 |
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