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TCR Signaling and CD28/CTLA-4 Signaling Cooperatively Modulate T Regulatory Cell Homeostasis
Foxp3(+) T regulatory cells (Tregs), conventional CD4(+)Foxp3(−) T cells, and CD8(+) T cells represent heterogeneous populations composed of naïve-phenotype (NP, CD44(low)) and memory-phenotype (MP, CD44(high)) subpopulations. NP and MP subsets differ in their activation state, contribution to immun...
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| Veröffentlicht in: | J Immunol |
|---|---|
| Hauptverfasser: | , , , |
| Format: | Artigo |
| Sprache: | Inglês |
| Veröffentlicht: |
2017
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| Schlagworte: | |
| Online Zugang: | https://ncbi.nlm.nih.gov/pmc/articles/PMC5296272/ https://ncbi.nlm.nih.gov/pubmed/28053234 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.4049/jimmunol.1601670 |
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